How big of an impact do asymptomatic people have on the dynamics of an epidemic?

Asymptomatic carriers serve as a potential source of transmission of epidemic diseases. Exposed people who develop symptoms only get tested and remain isolated in their homes or sometimes in hospitals when needed. In contrast, the asymptomatic individuals go untested and spread the disease silently as they roam freely throughout their entire infectious lifetime. The work intends to explore the role of asymptomatic carriers in the transmission of epidemic diseases and investigate suitable optimal control strategies. We propose a SEIAQR compartmental model subdividing the total population into six different compartments. To illustrate the model's implication, we estimate the number of asymptomatic individuals using COVID-19 data during June 9–July 18, 2021 from Bangladesh. We then analyze the model to explore whether the epidemic subsides if the asymptomatic individuals are tested randomly and isolated. Finally, to gain a better understanding of the potential of this unidentified transmission route, we propose an optimal control model considering two different control strategies: personal protective measures and isolation of asymptomatic carriers through random testing. Our results show that simultaneous implementation of both control strategies can reduce the epidemic early. Most importantly, sustained effort in identifying and isolation of asymptotic individuals allows relaxation in personal protective measures. © 2023

Gaseous and Particulate Pollution in the Wu-Chang-Shi Urban Agglomeration on the Northern Slope of Tianshan Mountains from 2017 to 2021

Rapid social development has led to serious air pollution problems in cities, and air pollutants, including gaseous pollutants and particulate matter, have an important impact on climate, the environment, and human health. This study analyzed the characteristics, potential sources, and causes of air pollution in the Wu-Chang-Shi urban cluster. The results showed that NO2, CO, SO2, PM10, and PM2.5 had a tendency to decrease, while O-3 showed an increasing trend. The concentrations of SO2, NO2, CO, PM2.5, and PM10 showed the highest values in winter and the lowest values in summer, with similar seasonal variations. However, the concentration of O-3 was highest in the summer and lowest in the winter. Compared with the pollutant concentrations in other Chinese cities, PM2.5, PM10, and NO2 are more polluted in the Wu-Chang-Shi urban. Meteorological factors have a greater impact on pollutant concentrations, with higher concentrations of major pollutants observed when wind speeds are low and specific wind directions are observed, and higher secondary pollutant O-3 concentrations observed when wind speeds are low and specific wind directions are observed. The backward trajectory and concentration weighting analysis show that the particulate pollutants in the Wu-Chang-Shi urban in winter mainly come from Central Asia and surrounding cities. O-3 showed an increasing trend before and after the novel coronavirus outbreak, which may be related to changes in NOX, volatile organic compounds, and solar radiation intensity, and the concentrations of SO2, NO2, CO, PM10, and PM2.5 showed an overall decreasing trend after the outbreak and was smaller than before the outbreak, which is related to the reduction of industrial and anthropogenic source emissions during the outbreak.

Aerosol Characteristics during the COVID-19 Lockdown in China: Optical Properties, Vertical Distribution, and Potential Source

The concentration changes of aerosols have attracted wide-ranging attention during the COVID-19 lockdown (CLD) period, but the studies involving aerosol optical properties (AOPs) are relatively insufficient, mainly AOD (fine-mode AOD (AODf) and coarse-mode AOD (AODc)), aerosol absorption optical depth (AAOD), and aerosol extinction coefficient (AEC). Here, the remote-sensing observations, Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2) products, backward-trajectory, and potential-source-contribution models are used to assess the impact of AOPs, vertical distribution, and possible sources on the atmosphere environment in North China Plain (NCP), Central China (CC), Yangtze River Delta (YRD), Pearl River Delta (PRD), and Sichuan Basin (SB) during the CLD period. The results demonstrate that both AOD (MODIS) and near-surface AEC (CALIPSO, <2 km) decreased in most areas of China. Compared with previous years (average 2017–2019), the AOD (AEC) of NCP, CC, YRD, PRD, and SB reduced by 3.33% (10.76%), 14.36% (32.48%), 10.80% (29.64%), 31.44% (22.68%), and 15.50% (8.44%), respectively. In addition, MODIS (AODc) and MERRA-2 (AODc) decreased in the five study areas compared with previous years, so the reduction in dust activities also contributed to improving regional air quality during the epidemic. Despite the reduction of anthropogenic emissions (AODf) in most areas of China during the CLD periods, severe haze events (AODf > 0.6) still occurred in some areas. Compared to previous years, there were increases in BC, OC (MERRA-2), and national raw coal consumption during CLD. Therefore, emissions from some key sectors (raw coal heating, thermal power generation, and residential coal) did not decrease, and this may have increased AODf during the CLD. Based on backward -rajectory and potential source contribution models, the study area was mainly influenced by local anthropogenic emissions, but some areas were also influenced by northwestern dust, Southeast Asian biomass burning, and marine aerosol transport. This paper underscores the importance of emissions from the residential sector and thermal power plants for atmospheric pollution in China and suggests that these sources must be taken into account in developing pollution-mitigation plans. [ FROM AUTHOR] Copyright of Remote Sensing is the property of MDPI and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

Exhaled Breath Condensate Study for Biomarkers Discovery

Biomarkers seem to play an important role in understanding various diseases’ nature, course and management, including respiratory ones. Yet, discovering verifiable and validated ones, that are useful in pulmonology, is challenging and constant. A special body specimen that has been characterized as a matrix of biomarkers, is the exhaled breath condensate (EBC). It is a fluid resulting from freezing the exhaled air. Water is its main constituent. The rest is a rich mix of water-soluble volatile compounds and aerosol droplets of airway lining fluid. The droplets carry non-volatile organic compounds. Their concentration is very small and the techniques applied to measure it are very accurate and sensitive. The content of the exhaled breath condensate reflects important processes taking place in the lungs, such as inflammation and oxidative stress, which are the basis of respiratory diseases’ pathophysiology. It seems that it has a role in diagnosis, monitoring, stratification and therapy of respiratory diseases, including COVID19. This paper presents information on exhaled breath condensate and highlights its importance as a potential source of biomarkers. © 2022, Springer Nature Switzerland AG.

Temporal variation of gaseous elemental mercury in a northern coastal city in China: Monsoon and COVID-19 lockdown effects

Continuous measurements of gaseous elemental mercury (GEM) were conducted in Qingdao from March 2020 to March 2021. The average concentration of GEM was (2.39 ± 1.07 ng/m3) with a variation range of 0.27–10.78 ng/m3. GEM exhibited a clear pattern of daily variation, with daily peaks occurring between 11:00–13:00. GEM concentrations were higher in winter (2.80 ± 1.28 ng/m3) than that in summer (2.18 ± 1.05 ng/m3). The high winter concentrations were related to coal-fired heating and the increased frequency of polluted weather in northern China. Principal component analysis showed that the main factors affecting GEM concentration were fossil fuel combustion, natural source release and atmospheric diffusion conditions. The anthropogenic emission sources were the main source of GEM in spring and winter, and natural sources of GEM was large in summer. The potential source contribution function suggested that North and Central China were the main potential sources of GEM, and there were large differences in the potential sources of GEM in different seasons. Comparing the GEM in the same time periods in 2018, 2020, and 2021, government policies, temporary lockdown measures for the COVID-19 epidemic, and urban village renovation led to a decreasing trend of GEM concentrations. This study contributes to a better understanding of the effects of long-range transport of air masses and anthropogenic emissions on atmospheric mercury in eastern coastal cities and offshore areas.

Per- and Polyfluoroalkyl Substances (PFAS) in Facemasks: Potential Source of Human Exposure to PFAS with Implications for Disposal to Landfills

Facemasks are important tools for fighting against disease spread, including Covid-19 and its variants, and some may be treated with per- and polyfluoroalkyl substances (PFAS). Nine facemasks over a range of prices were analyzed for total fluorine and PFAS. The PFAS compositions of the masks were then used to estimate exposure and the mass of PFAS discharged to landfill leachate. Fluorine from PFAS accounted only for a small fraction of total fluorine. Homologous series of linear perfluoroalkyl carboxylates and the 6:2 fluorotelomer alcohol indicated a fluorotelomer origin. Inhalation was estimated to be the dominant exposure route (40%-50%), followed by incidental ingestion (15%-40%) and dermal (11%-20%). Exposure and risk estimates were higher for children than adults, and high physical activity substantially increased inhalation exposure. These preliminary findings indicate that wearing masks treated with high levels of PFAS for extended periods of time can be a notable source of exposure and have the potential to pose a health risk. Despite modeled annual disposal of 29-91 billion masks, and an assuming 100% leaching of individual PFAS into landfill leachate, mask disposal would contribute only an additional 6% of annual PFAS mass loads and less than 11 kg of PFAS discharged to U.S. wastewater. © 2022 American Chemical Society.

Design of a Smart Footwear Disinfecting Station for Crowded Premises

Since the first virus was identified in the early last century, many kinds of different viruses have been discovered until now that can harm a human being. One of these is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or well known as coronavirus, which has pushed the entire world into a deadly pandemic. The pandemic has been affecting public health, employment, lifestyle, and the entire food system. To protect our house, workplace, and heavily populated areas such as markets and hospitals from being infected by the virus, it needs to be stopped in every possible way to be spread. Footwear is one of the potential sources of contamination and possible carrier of the virus, especially if it touches an infected place or someone who has already infected sneezes or coughs nearby. Since most footwear is made of leather, rubber, and plastic, the virus can live on these for many days at room temperature. Even footwear can be a breeding ground for bacteria and viruses as it comes in contact with dirt and germs more than anything else. In this paper, a smart device for disinfecting footwear has been proposed for crowded premises. The sensing device will automatically sense the visitor’s presence at the entrance and will disinfect his footwear by spraying disinfecting agent underneath the footwear or foot. This disinfecting station will allow visitors to disinfect their footwear without stopping and will ensure effecting sanitization of the entire sole even if the sole has deep flex grooves or high heels. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.